---
listing_id: ML82059314
status: Active
price: 1248000
beds: 3
baths_full: 4
baths_half: 0
sqft_living: 1630
sqft_lot: 3500
lot_acres: 
year_built: 1895
property_type: Residential
property_subtype: Single Family Residence
address: "643 Grand Ave"
city: South San Francisco
state: CA
zip: 94080
county: "San Mateo County"
lat: 37.657367
lng: -122.421512
days_on_market: 3
hoa_fee: 
hoa_frequency: 
garage_spaces: 2
list_agent: "Jill Penna"
list_office: "Christie's International Real Estate Sereno"
list_agent_phone: "(415) 244-8630"
list_agent_license: 01895080
mls_source: MLSL
modified: 2026-08-30
transaction_type: buy
---

Home | San Mateo County | South San Francisco | 94080 | 643 Grand Ave

643 Grand Ave, South San Francisco, CA 94080

MLS: ML82059314 | Status: Active | Price: $1,248,000
Beds/Baths: 3 / 4
Property Type: Residential

Quick Facts

Beds Baths Sq Ft Sq Ft Lot Yr Built
3 4 1,630 3,500 1895

Upcoming Open Houses

Date Time Hosted By
Sunday, August 30 1:00 pm - 4:00 pm Jill Penna

Remarks

Ideally located near Downtown South San Francisco and the cities thriving biotech and life-sciences corridor, 643 Grand Avenue where space, comfort, and a remarkable garden setting come together in the heart of South San Francisco. 643 Grand Avenue offers a spacious and versatile layout with excellent access to major transportation and employment centers. The home features 3 bedrooms and 4 bathrooms, with a private full bathroom for each bedroom. Additional highlights include high ceilings, abundant natural light, hardwood floors, a full basement with ample storage, and a detached 2-car garage equipped with a 220-volt outlet for EV charging. The home also features a water purification system, tankless water heater, and water softener. The quaint lot includes a freshly manicured organic vegetable garden with sunflowers and offers potential for an ADU. Conveniently located near Downtown South San Francisco, Genentech, Caltrain, US-101, and I-280.

MLS Listing Information

Field Value
MLS # ML82059314
MLS Source MLSListings, Inc.
Days on Site 3

Features

Interior Features

Feature Details
Appliances Water Softener
Dining Room Dining Area in Living Room
Family Room No Family Room
Cooling None
Heating Central Forced Air

Exterior Features

Feature Details
Roof Shingle
Foundation Slab

Parking, School, and Other Information

Feature Details
Garage/Parking Detached, On Street, Garage: 2 Car(s)
Elementary District South San Francisco Unified
High School District South San Francisco Unified
Sewer Public Sewer
Water Public
Zoning RM0000

Contact Information

Jill Penna
Christie's International Real Estate Sereno
License #: 01895080
Phone: (415) 244-8630

Nearby Homes

Address Price Beds Baths Sq Ft Status
525 Larch Ave $1,275,000 4 2 1,630 Active
326 Armour Ave $1,198,000 3 3 1,790 Active
343 Alta Mesa Dr $1,478,000 3 2 1,870 Active
72 Wessix Ct $1,388,000 3 2/1 1,980 Active

Disclosures

©2026 MLSListings Inc. All rights reserved. All data, including all measurements and calculations of area, is obtained from various sources and has not been, and will not be, verified by broker or MLS. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information. Information provided is for personal, non-commercial use by the viewer and may not be redistributed without explicit authorization from MLSListings Inc.

Presently MLSListings.com displays Active, Contingent, Pending, and Recently Sold listings. Recently Sold listings are properties which were sold within the last three years. After that period listings are no longer displayed in MLSListings.com. Pending listings are properties under contract and no longer available for sale. Contingent listings are properties where there is an accepted offer, and seller may be seeking back-up offers. Active listings are available for sale.

This listing information is up-to-date as of August 30, 2026. For the most current information, please contact Jill Penna, (415) 244-8630.